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Morris Karmazyn Selected Research

N- (2- methyl- 4,5- bis(methylsulfonyl)benzoyl)guanidine

1/2011Expression of mitochondrial fusion-fission proteins during post-infarction remodeling: the effect of NHE-1 inhibition.
1/2004Inhibition and reversal of myocardial infarction-induced hypertrophy and heart failure by NHE-1 inhibition.
12/2003Aldosterone increases NHE-1 expression and induces NHE-1-dependent hypertrophy in neonatal rat ventricular myocytes.

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Morris Karmazyn Research Topics

Disease

43Hypertrophy
05/2021 - 08/2003
21Heart Failure
05/2021 - 08/2003
16Cardiomegaly (Heart Hypertrophy)
05/2021 - 10/2006
12Obesity
01/2016 - 08/2003
9Heart Diseases (Heart Disease)
09/2014 - 08/2003
7Ischemia
09/2009 - 04/2002
4Infarction (Infarctions)
09/2018 - 01/2004
4Body Weight (Weight, Body)
01/2013 - 09/2002
4Acidosis
04/2008 - 04/2002
3Hypertension (High Blood Pressure)
01/2021 - 01/2005
3Mitochondrial Diseases (Mitochondrial Disease)
04/2019 - 09/2009
3Myocardial Infarction
08/2012 - 01/2004
3Hyperglycemia
01/2004 - 09/2002
2Diabetes Mellitus
04/2019 - 01/2018
2Reperfusion Injury
09/2018 - 02/2003
2Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
12/2014 - 05/2014
2Myocardial Ischemia (Ischemic Heart Diseases)
08/2012 - 09/2002
2Inflammation (Inflammations)
08/2012 - 07/2008
2Hypoxia (Hypoxemia)
04/2009 - 02/2003
2Cardiovascular Diseases (Cardiovascular Disease)
08/2006 - 01/2005
1Insulin Resistance
04/2019
1Left Ventricular Dysfunction
12/2016
1Heart Arrest (Cardiac Arrest)
08/2013
1Myocardial Stunning (Stunned Myocardium)
08/2012
1Cardiomyopathies (Cardiomyopathy)
08/2010

Drug/Important Bio-Agent (IBA)

22LeptinIBA
04/2019 - 08/2003
12Phenylephrine (Neo-Synephrine)FDA LinkGeneric
12/2014 - 11/2004
11Proteins (Proteins, Gene)FDA Link
04/2019 - 01/2004
8Atrial Natriuretic Factor (ANF)IBA
09/2014 - 01/2004
7Sodium-Hydrogen ExchangersIBA
01/2018 - 04/2002
7Protein Isoforms (Isoforms)IBA
12/2014 - 06/2006
6Mitogen-Activated Protein KinasesIBA
12/2011 - 08/2003
6Endothelin-1 (Endothelin 1)IBA
07/2009 - 09/2002
5Angiotensin IIIBA
05/2021 - 12/2004
5CalcineurinIBA
04/2019 - 01/2011
5SodiumIBA
01/2010 - 09/2002
5HydrogenIBA
01/2010 - 09/2002
4AdipokinesIBA
01/2016 - 07/2008
4Sodium-Hydrogen Exchanger 1IBA
12/2014 - 10/2006
4Adenosine (Adenocard)FDA LinkGeneric
09/2014 - 01/2005
4Peptides (Polypeptides)IBA
11/2013 - 08/2003
4CalciumIBA
12/2012 - 02/2003
4cariporideIBA
07/2007 - 04/2002
3Glucose (Dextrose)FDA LinkGeneric
05/2021 - 07/2007
3GinsenosidesIBA
01/2021 - 10/2017
3Adrenergic Receptors (Adrenergic Receptor)IBA
12/2016 - 12/2004
3Y 27632IBA
01/2014 - 01/2008
3p38 Mitogen-Activated Protein KinasesIBA
07/2012 - 01/2008
3Mitochondrial Permeability Transition PoreIBA
01/2011 - 06/2009
3N- (2- methyl- 4,5- bis(methylsulfonyl)benzoyl)guanidineIBA
01/2011 - 12/2003
3rho-Associated KinasesIBA
01/2008 - 10/2006
2Calcineurin InhibitorsIBA
04/2019 - 12/2012
2Tacrolimus (Prograf)FDA LinkGeneric
04/2019 - 12/2012
2Conditioned Culture MediaIBA
01/2016 - 04/2009
2latrunculin BIBA
01/2014 - 10/2006
2Purinergic P1 Receptors (Adenosine Receptor)IBA
01/2014 - 01/2005
2Small Interfering RNA (siRNA)IBA
01/2013 - 10/2008
2Leptin ReceptorsIBA
12/2011 - 07/2008
2Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
06/2011 - 09/2007
2Adenosine Triphosphate (ATP)IBA
09/2009 - 03/2003
2Messenger RNA (mRNA)IBA
07/2009 - 02/2003
2Phosphotransferases (Kinase)IBA
10/2008 - 10/2006
2Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
01/2008 - 12/2005
2Bosentan (Tracleer)FDA Link
07/2007 - 09/2002
2Biological ProductsIBA
08/2006 - 08/2003
2Endothelins (Endothelin)IBA
08/2006 - 12/2005
2Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
01/2004 - 09/2002
1Fatty Acids (Saturated Fatty Acids)IBA
05/2021
1Insulin (Novolin)FDA Link
04/2019
1Blood Glucose (Blood Sugar)IBA
04/2019
1Cardiotonic Agents (Cardiac Stimulants)IBA
09/2018
1radix ophiopogonis drug combination radix ginseng fructus schizandrae (Shen Mai)IBA
10/2017
1CatecholaminesIBA
12/2016
1Isoproterenol (Isoprenaline)FDA LinkGeneric
12/2016
1Adrenergic Agents (Adrenergic Drugs)IBA
12/2016
1AdiponectinIBA
01/2016
1Pharmaceutical PreparationsIBA
12/2014
1Alizarin Red SIBA
09/2014
1Alpha-Ketoglutarate-Dependent Dioxygenase FTOIBA
01/2013
12- (2- (4- (4- nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonateIBA
12/2012
1CalpainIBA
08/2012
1Drinking WaterIBA
07/2012
1Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA
12/2011
1Protein Kinases (Protein Kinase)IBA
12/2011
1Rho Guanine Nucleotide Exchange FactorsIBA
12/2011
1Antihypertensive Agents (Antihypertensives)IBA
10/2011
1Natriuretic PeptidesIBA
12/2010
1UlaritideIBA
12/2010
1Cyclic GMPIBA
12/2010
1A-factor (Streptomyces)IBA
05/2010
1Purinergic P1 Receptor AgonistsIBA
05/2010
1GlycosidesIBA
01/2010
1Cardiac GlycosidesIBA
01/2010
1Nitric Oxide (Nitrogen Monoxide)FDA Link
12/2009

Therapy/Procedure

6Ligation
12/2014 - 01/2004
3Therapeutics
10/2017 - 05/2014
2Resuscitation
08/2013 - 04/2002
1Coronary Artery Bypass (Coronary Artery Bypass Surgery)
09/2018
1Operative Surgical Procedures
09/2018
1Drug Therapy (Chemotherapy)
01/2011